Issue

If you wish to run a 32-bit web application under a Windows x64 VPS then you must switch IIS to run in 32-bit mode.

Solution

IIS 6.0 is able to run 32-bit Web applications on 64-bit Windows using the Windows-32-on-Windows-64 (WOW64) compatibility layer.

To enable IIS 6.0 to run 32-bit applications on 64-bit Windows

1. Open a command prompt and navigate to the %systemdrive%\Inetpub\AdminScripts directory.
2. Type the following command:
   

   cscript.exe adsutil.vbs set W3SVC/AppPools/Enable32BitAppOnWin64 "true"

   
   
3. Press ENTER.